9 Summary Infusion therapy is administered across all health care settings. When patients are stable in the acute care setting yet still require ongoing infusion therapy, the most appropriate alternative setting should be selected. Increasingly, infusion therapies are safely initiated in a non-acute care setting without prior hospitalization. The patient’s specific infusion therapy needs along with functional and cognitive status, availability of caregiver or family support, home environment, and patient and provider preferences are important factors influencing the optimal infusion setting. Regardless of the setting, the role of the infusion nurse is essential in ensuring the best possible outcome for the patient. Bibliography American Nurses Association. ANA’s Principles for Nurse Staffing. 2nd ed. Silver Springs, MD: ANA 2012. Gorski L. Fast Facts for Nurses About Home Infusion Therapy: The Expert’s Best-Practice Guide in a Nutshell. New York, NY: Springer Publishing Company 2017. Gorski L, Hadaway L, Hagle ME, McGoldrick M, Orr M, Doellman D. Infusion therapy standards of practice. J Infus Nurs. 2016 39(suppl 1):S1-S159. Gorski L, Miller C, Mortlock N. Infusion therapy across the continuum. In: Alexander M, Corrigan A, Gorski L, Hankins J, Perucca R, eds. Infusion Nursing: An Evidence- Based Approach. 3rd ed. St Louis, MO: Saunders/Elsevier 2010:109-126. Tice AD, Rehm SJ, Dalovisio JR, et al. Practice guidelines for outpatient parenteral antimicrobial therapy practice. Clin Infect Dis. 2004 38(12):1651-1672.